our Project
CLIMADE INDO-PACIFIC
For CLIMADE Indo-Pacific, the overarching vision is to research and respond to their epidemics. The Indo-Pacific area is experiencing large arboviral epidemics. Australia scientists from University of Sidney will also support the African, Asian and American programs with meta genomics and data analysis methods.
Aim 1. Genomics Surveillance of arboviruses and emergent pathogens
Populations of viruses in an host can be very diverse and just as the behaviour of a population of humans can be very different to the behaviour of individuals in them, populations of viruses behave differently to the behaviour of individuals in them. This diversity may provide a survival advantage to the virus and it also may regulate the severity of the symptoms in an infected host. This study will provide important new information that will drive vaccine strategies and public health policy.
Aim 2. Development and application of meta genomics methods for identification of new pathogens and variants
• Next generation and/or metagenomic sequencing) of samples received from country partners. Sequencing will encompass both historical biobanked samples and prospective samples accessed by leveraging existing sample referral systems.
Description
initial Project
Description
Size : 1,000 genomes
Location : Australia
Principal Investigators : Prof. Edward C Holmes, Dr. Tanya Golubchik and Dr. Rebecca Rockett
Project start : 2023 January
Project finish : 2024 August
Value : $1m (funded by Australia’s National Health and Medical Research Council)
the result
OUTCOMES
- Short-term – closing the critical knowledge gaps in arbovirus genomic epidemiology and opening up sampling pipelines to identify hotspots and inform the resource allocation, countermeasures, and policy decisions of public health institutes and ministries of health.
- Medium-term – engaging in dialogue with ministries of health around the report produced from extensive review of arbovirus-related research activities in Inso-pacific area and climate-related disease forecasting activities prior to COP28, as well as refining and optimizing processes for sampling and translating science to public health action.
- Long-term – creating sustainable capacity to identify and monitor pathogens in real time by training personnel from national public health institutes to sequence arboviruses and other emergent viruses/
Let’s Get in Touch
Contact details
E-mails: edward.holmes@sydney.edu.au, tanya.golubchik@sydney.edu.au, rebecca.rockett@sydney.edu.au
Addresses: University of Sydney, Sydney, Australia.
Opening hours:
Monday — Friday: 8:00 – 18:00
Saturday — Sunday: Closed
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